t-OctNSO

£95.00£395.00

A novel sulfinylamine reagent for the two-stage synthesis of diverse sulfondiimines and sulfoximines via organometallic reagent addition followed by catalysed imination or oxidation of the sulfilimine intermediate.

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Description

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Cortex Organics have partnered with Professor Michael Willis at the University of Oxford (https://willisgroup.web.ox.ac.uk/) to commercialise the novel, air stable sulfinylamine reagent, t-OctNSO. This versatile reagent combines with Grignard and organolithium reagents to allow, following catalysed imination or oxidation of the sulfilimine intermediate and t-octyl group removal, access to a range of medicinally relevant sulfondiimines and sulfoximines. For more information, see:

https://pubs.acs.org/doi/10.1021/jacs.9b06831

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Quantity

500mg, 1000mg, 2000mg, 5000mg